Use variety of commands, the main command is /regen:

1. /regen create - to create a region
2. /regen delete - to delete a region
3. /regen list - to list all the regions
4. /regen setspawn - to teleport the players to the location after the regen is complete
5. /regen corner1 - to set the corner 1 of the region
6. /regen corner2 - to set the corner 2 of the region
7. /regen regenerate - to regenerate the region without messing with schedule.

Depends on: FastAsyncWorldEdit